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Obes Surg 29(1):314 AziziKia H et al (2024) Periprocedural changes of serum biomarkers in predicting complications following bariatric surgery for obesity: systematic review and meta-analysis

Thyroid C-Cell Tumors: In mice and rats, tirzepatide (the active ingredient in Zepbound and Mounjaro) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

Of interest, in the study design, the company states that included individuals had a flexible dosing protocol [125], which could have accounted for not meeting the desired 25% body weight reduction target