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However, GCL is upregulated by estradiol, leading to a higher concentration of glutamyl-cysteine (Glut-Cys) in females, thereby driving increased GS flux

Using multiple approaches from the cell to the whole organism and extensively examine the role of various neuroendocrine signaling systems (e.g., GLP-1, leptin, amylin, CCK, serotonin, glutamate, and dopamine) in peripheral and central control of food intake and body weight regulation

Carnitine is especially important for heart muscle to function properly

In this context, routine assessment of BC and functional parameters should become a clinical priority, shifting the focus from weight alone to the broader concept of quality weight loss