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These include the use of Smoothened (Smo) agonists to activate Shh signaling, as well as small-molecule modulators of intraflagellar transport (IFT) proteins to restore ciliary trafficking and structural integrity [263268]

Pharmacological interaction between 3, 4-methylenedioxymethamphetamine (ecstasy) and paroxetine: pharmacological effects and pharmacokinetics

Abstract Hypertension, or persistently elevated blood pressure, affects about one third of the adult population worldwide and causes approximately 8.5 million deaths annually

Neuroprotective and neurotrophic actions: MC4 signaling is implicated in the regeneration and protection of peripheral nerves, as observed in experimental injury and neuropathy models 3