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[25] This is the same broader gutbrain axis that connects your digestive tract to mood and appetite, which is why the state of your gut can influence how satisfied you feel after a meal not just how you digest it

The table lists nausea of any grade at 25 to 48 percent in the SUSTAIN trials for semaglutide and 25 to 50 percent in the SURMOUNT trials for tirzepatide, calling both dose-dependent and typically resolving within four to eight weeks

Of these, 20 were assigned to receive 5 mcg of subcutaneous exenatide twice daily for 1 month, followed by 10 mcg twice daily for 11 months, while 24 were placed in the control group