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Although no head to head trials comparing tirzepatide to semaglutide 2mg exists, an adjusted indirect treatment comparison study aimed to compare these two agents based on the results from SURPASS 2 and SUSTAIN FORTE

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Intriguingly, breast cancer cells in metastatic lung tumors experience higher magnitude of solid stress compared to those in the primary tumor, underscoring the key role of the local microenvironment in modulating solid stress during cancer progression [116]