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Limitations and Prospects of Carnitine for the Treatment of NAFLD Despite promising results, the studies on the role of L-carnitine in NAFLD, listed in Tables 1, 2, face many limitations

This SCFA-mediated reinforcement of intercellular junctions reduces the risk of increased intestinal permeability, commonly referred to as leaky gut, a pathological condition that enables the translocation of luminal antigens and other deleterious molecules into the systemic circulation (170)

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However, further characterization of the molecular targets within the interconnected AD and PD pathways is still required