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Under ICH conditions, iron is transported to the extracellular space through the iron export protein FPN in microglia, causing a large amount of toxic iron to enter the brain tissue (Hvidberg et al., 2005)

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doi: 10.1086/502205 50 VonrheinC.FlensburgC.KellerP.SharffA.SmartO.PaciorekW.et al

What happens if I inject Lipo C subcutaneously instead of intramuscularly? Subcutaneous administration reduces bioavailability by approximately 30% because lymphatic absorption is slower and methionine enters systemic circulation without immediately reaching the liver, where its lipotropic effects occur