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The data from the two centers were presented separately in a systematic review by Pi et al

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The symptoms of tobacco withdrawal include physical and mental challenges that individuals face when they attempt to quit using tobacco products, according to an article by the Centers for Disease Control and Prevention titled 7 Common Withdrawal Symptoms. As the body adjusts to the absence of nicotine, these withdrawal symptoms manifest in various physical and mental distress and issues, making the cessation process uncomfortable and challenging