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Beyond nicotine, aerosols contain toxic additives such as propylene glycol, glycerol, flavoring agents, and metals released from heating coils, which elevate respiratory and cardiovascular risks and may cause long-term damage to the developing heart and lungs 6-8

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For example, individuals experiencing anhedonia (whether as part of drug addiction or due to some other disorder like depression) display decreased activity in the ventral striatum, orbitofrontal cortex, and prefrontal cortex, as well as various abnormalities in dopamine signaling

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