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Since June 2019, more than 1,000 cases of vaping-associated lung injury have been reported.2 The reason for the sudden onset of this new epidemic remains poorly understood, though increasing evidence suggests that the syndrome may be related to use of vaporizer cartridges modified with THC or other additives

"We are confronting a giant, like the fight between David and Goliath

To understand the underlying mechanism, we investigated the impact of colchicine on the activation of NF-B, MAPKs, and mTOR pathways in smoke-condensate-treated endothelial cells

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