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A ten-year study was completed by Donald R

Specifically, CO levels in rooms where shisha was smoked were found to be five times higher than in rooms where cigarettes were smoked, while CO levels in rooms next to where shisha was smoked were nearly four times higher compared to rooms next to where cigarettes were smoked

2016, titled Effects of Marijuana Use on Brain Structure and Function: Neuroimaging Findings from a Neurodevelopmental Perspective, has shown that chronic marijuana use leads to alterations in brain structure, particularly in areas associated with memory and learning