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The latter not only rolled the cigar at his factory, but also grew all the Nicaraguan tobaccos used in the blend, including the extra-fermented oscuro wrapper, which is the cigar's defining leaf

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The 18 reports of women showed that one cigarette per day had 31% (interquartile range 2-46%) of the excess risk of 20 cigarettes per day (pooled relative risks 1.57 v 2.84), and smoking five cigarettes per day had 43% (14-55%) the excess risk (relative risk 1.76) (fig 3