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Indeed, although many studies have clearly shown that several interventions including pharmacological therapy and lifestyle modifications improve endothelial function under the condition of relatively mild vascular endothelial dysfunction [8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35], we have shown that advanced endothelial dysfunction is not reversible even by appropriate pharmacological therapy [94]

It lies about its product and seems to care less that, as a result of a settlement, it must advertise that it deliberately deceived the American public, that 1200 people die every day from smoking, and that second hand smoke kills over 38,000 Americans a year. The industry calls these statements forced confessions. The fact is, the industry seems willing to undertake any cost, and violate any agreement, to keep selling the poisonous weed