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Canagliflozin is primarily glucuronidated by UGT1A9 and UGT2B4, forming inactive O-glucuronide metabolites, with minimal oxidative metabolism by CYP3A4 (Invokana, 2024)

[DOI] [PubMed] [Google Scholar] Pickworth WB, Fant RV, Nelson RA, Rohrer MS, Henningfield JE

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