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Studies have shown that these chemicals can be toxic to fish

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This is mainly due to cellulose acetate, a plastic that takes more than 10 years to decompose and which is one of the main components of the filter

The ROS produced are converted to peroxynitrite, which has a very strong cytotoxic effect when combined with NO, resulting in direct damage to vascular wall cells and a decrease in the biological activity of NO in vascular endothelial cells and vascular smooth muscle cells [68]