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This revealed significant parthanatos activation occurs with exposure to eight or greater cigarettes, but not after four cigarettes (Fig

Other studies in adults have also shown that smoking has a negative impact on the postoperative outcome of nasosinusal endoscopic surgery when assessed under the viewpoint of symptoms, quality of life scores, endoscopic analysis and CT-scan findings.32,33,34 In the pediatric population, Kim et al.35, retrospectively assessed 97 patients submitted to paranasal sinuses surgery, and showed that children exposed to cigarette smoke had a worse postoperative outcome based on endoscopic analysis

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