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E-cigarettes aerosol often includes nicotine, flavoring such as diacetyl, cancer-causing chemicals and heavy metals like nickel, tin and lead, according to the CDC.The CDC has also linked e-cigarettes to slowing adolescent brain development, which can continue into the early to mid-20s

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Look for verified tar and nicotine reduction percentages, typically ranging from 20% to 70% depending on filter design and material

The big limitation of the paper is that it assumes that e-cigs are so much safer than [cigarettes] that the authors dont need to consider any continuing use of e-cigs as a complication