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Led by Moon-Shong Tang, PhD, an NYU School of Medicine researcher, the study also found that 23 of 40 mice (57.5 percent) exposed to e-cigarette smoke developed bladder hyperplasia, genetic changes that make cells more likely to multiply, and a step toward abnormal tissue growth seen in cancer

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The electronic devices, which contain liquid nicotine that is heated into a vapour and inhaled, are said to avoid the harm caused by tobacco smoke.But the British Heart Foundation says the devices could not be assumed to be risk-free. The charity also wants more research into the safety of long-term use.Public Health England nevertheless encouraged smokers to switch to e-cigarettes last year, saying they were 95 percent safe.The claim drew fire when it emerged that it came from scientists funded by the e-cigarette industry