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We previously reported a systematic review on IQOS conducted on 8 November 2021, on Web of Science, PubMed, and Scopus using the terms heated tobacco product, heat-not-burn, IQOS, and tobacco heating system 17

Two multiple linear regression analyses were also conducted: the first to identify predictors of short-term reduction in FTND score at the end of the program, and the second to assess whether engagement with program tools predicted the maintenance of FTND score reduction at five months

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It is among many chemicals found in cigarette smoke classified as carcinogenic or potentially carcinogenic to humans