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Nicotine is a psychoactive chemical, a central nervous system and brain dopamine pathway stimulant

This discrepancy is partly attributable to the influence of prostate-specific antigen (PSA) screening, which has led to widespread overdiagnosis of indolent tumors, thereby obscuring true etiological relationships

Not long after John Rolfe successfully introduced tobacco production to Virginia, planters discovered that when tobacco was shifted away from the river bottoms and ventured into sandy soils found closer to the ocean or clay soils in the high necklands and piedmont, their tobacco was not as dense and aromatic as in the sweet-scented areas

The science illuminates a significant potential risk with vaping, a necessary consideration in the larger conversation about its health impacts