The decision allows these products, which have been available in the US since January 2025, to be marketed with a claim stating that using Zyn instead of cigarettes puts users at a lower risk of mouth cancer, heart disease, lung cancer, stroke, emphysema, and chronic bronchitis
In addition, PG with nicotine caused increased macrophage and CD4 + /CD8 + T-lymphocytes cell counts in BALF compared to air control, but these effects were ameliorated when animals were sub-chronically exposed to PG alone [42]
[DOI] [PubMed] [Google Scholar] Freedman DM, Sigurdson AJ, Rajaraman P, Doody MM, Linet MS, Ron E
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