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For instance, FUT8 deficiency in mouse embryonic fibroblasts results in enhanced Wnt/-catenin signaling and upregulation of Wnt target genes, indicating that core fucosylation may normally act to constrain pathway activation [117]
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The report showed that by 2030, the European region, consisting of 53 countries, is projected to have the highest rates globally with a prevalence of just over 23 per cent
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