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Finally, optogenetically increasing or decreasing VTA DA neuron activity shifted individual strategies, recapitulating the results from nicotine-exposed mice and computational modeling

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2 Methods 2.1 Types of tobacco products Viewing of tobacco products use in China, this study examined five types of tobacco products: combustible cigarettes (CCs), e-cigarettes (ECs), heated tobacco products (HTPs), oral nicotine products (ONPs) and tobacco-free oral nicotine pouches (TFONPs)