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The appropriate dose depends on the individual's smoking habits: Individuals who smoke more than 10 cigarettes per day should begin with the 21 mg patch. After approximately 8 to 12 weeks, the dose should be gradually reduced to eventually discontinue use altogether.Instructions for Use: Apply the patch to a clean, dry, hairless area on the upper bodytypically the upper chest, upper arm, shoulder, back, or inner arm. Avoid applying the patch to irritated, oily, scarred, or damaged skin. Remove the patch from its protective packaging and peel off the backing strip. Press the patch firmly onto the skin for 1020 seconds to ensure secure adhesion, particularly around the edges. Wash hands thoroughly with soap and water after application to remove any residual nicotine. Rotate the patch application site daily to prevent skin irritation