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Differentially expressed genes between smoke treated and sham treated cells were analyzed with JMP 13 statistical software, which performs individual t tests for each gene and applies a BenjaminiHochberg correction (FDR 4 months were inoculated into mice that had also been chronically exposed to cigarette smoke and the smoke exposure was continued in vivo until completion of the experiment

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According to IAFA, a multi-stage (i.e., two stages) stratified area probability sample (54) of 3,524 individuals (i.e., elements) selected across 60 schools (i.e., clusters or secondary sampling units) within 10 geostatistical areas (i.e., primary sampling units) was randomly selected from a preestablished school system sample frame

3 There are also rapid and ongoing changes in e-cigarette technology that may improve the impact on smoking cessation (e.g., by delivering nicotine more quickly and in higher doses to better approximate nicotine delivery by cigarettes)