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Rub all parts of your hands including your palms, between fingers, thumbs, backs, wrists, fingertips, and nails

In the mid-1900s, cocaine hydrochloride was finally extracted from the coca leaves, which is the pure chemical thats responsible for the plants intoxicating qualities However, it wasnt until the 70s and 80s that cocaine use exploded

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Nicotine is metabolized in the liver by the cytochrome P450 enzymes CYP2A6 and CYP2B6 to form a variety of metabolites, 70 to 80% of which are converted to cotinine that is then excreted in the urine [102]