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The human microbiota, composed of bacteria, fungi, archaea, and other microorganisms, plays a critical role in regulating immune responses, metabolism, and defense against harmful pathogens

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Using the United States (U.S.) as an example, we outline the leading themes that have arisen in response to these two questions

The other model instead added a continuous covariate for time, as measured by the number of years between period midpoints relative to the first period, and produced a p-value from a t-test to assess a linear ANA time trend