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EVIDENCE SUMMARY Bupropion is the only Food and Drug Administration (FDA)-approved antidepressant recommended as a first-line pharmacologic agent to assist with smoking cessation, based in part on a meta-analysis of 44 placebo-controlled RCTs (13,728 patients), which found that bupropion had a relative risk (RR) of 1.62 for smoking cessation compared with placebo (95% confidence interval [CI], 1.49-1.76)

doi: 10.2174/1381612822666151109111712 120

The Watertown Plan Commission this month rejected a proposed downtown location, but Peters is considering a different site in that community, as well as possible clubs in West Milwaukee, Racine and Fond du Lac