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A 2023 study in Tobacco Control found that flavoring chemicals in pouches impair periodontal immune responses and increase penetration of nitrosamines the flavors themselves may cause harm independent of nicotine

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20 reported that children exposed both prenatally and postnatally and those exposed only postnatally had more rhinitis compared with children with non-smoking parents, but they did not show that prenatal tobacco smoke exposure or exposure in early childhood was of significant importance for rhinitis

Complex and interrelated factors ranging from socioeconomic and environmental influences to individual lifestyle factors contribute to obesity