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The smoking-attributable mortality rate is 18 percent higher for Black people (338 deaths per 100,000 population, versus 286 for whites)

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The speed of nicotine delivery is a fundamental difference between cigarettes and nicotine replacement therapy (NRT) products which deliver nicotine at lower and slower subaddictive rates

The introduction of low-nitrosamine snus in the late 1990s made the product even more appealing to those seeking a less harmful nicotine source