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Nothere are plenty of guidelines to smoking cessation, replete with information on nicotine replacement therapy, other pharmacotherapies such as varenicline and bupropion, appropriate behavioral strategies, and advice on combining approaches.28-31 In many cases, these strategies are underused32our need for better smoking cessation may simply reflect the need to use the tools we already have

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This is known to convert nicotine into nitrosamines such as N-nitrosonoricotine (NNN) and nicotine-derived nitrosamine ketone (NNK), which are proven carcinogens in mice and humans