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Conclusion In summary, disposable vapes are legal in California but heavily regulated to ensure public health and those regulations include protecting children

Additionally, distribution channels are also heavily controlled by existing players, which can make it difficult for new entrants to gain access to the market

Key to this approach are (i) the use of agreed reference products for comparison, ideally authorized MRTPs, and (ii) bridging methodologies that allow to compare a cMRTP with the reference products based on a limited number of studies (see challenge 4)

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