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[45] Contraindications [edit] A hormonal IUD should not be used by people who: Are, or think they may be, pregnant [24] Have abnormal vaginal bleeding that has not been explained [24] (controversial) [46] Have untreated cervical or uterine cancer [24] Have, or may have, breast cancer [24] Have abnormalities of the cervix or uterus [47] (controversial) [46] Have had pelvic inflammatory disease within the past three months [24] Have had an STI such as chlamydia or gonorrhea within the past three months [24] Have liver disease or tumor [47] Have an allergy to levonorgestrel or any of the inactive ingredients included in the device [47] Insertion of an IUD is acceptable after a dilation and evacuation (D&E) abortion (second-trimester abortion), but may be associated with a higher expulsion rate

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Regional grey and white matter changes in heavy male smokers