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Belgium : Minors can purchase nicotine-free e-liquids at 16, although they cannot buy nicotine-containing products until they are 18

Future research to identify other susceptibility factors, such as genes that modify carcinogen metabolism or DNA repair, will need to be substantially larger and to quantify lifetime tobacco exposure with more precision than have past studies in order to distinguish gradations in risk due to exposure from those caused by genetic susceptibility

Smokeless and other noncigarette tobacco use and pancreatic cancer: a case-control study based on direct interviews

Socioeconomic Factors: Tobacco use is higher among rural, illiterate, and lower-income populations