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While some studies support the claim that limiting flavored tobacco product sales reduces teenage use, other research, including by Brown Universitys School of Public Health, found that vapes were not a gateway to cigarette use among teens, and stressed the importance of cessation tools like nicotine gum and vapes to help cigarette smokers quit

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CSM also increased the expression of SARS-CoV-2-induced inflammatory cytokines such as IL-6, which might further lead to worsening outcome