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A 2012 systematic review and meta-analysis that included 13 prospective cohort studies with 56691 participants found a significant positive association between active smoking and risk of metabolic syndrome (pooled relative risk, RR=1.26

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Consequently, CBs in soil and aquatic environments not only pose a toxic potential for microbial community and aquatic lifeforms, but also cause mild allergic reactions and serious human health issues such as cancer, diabetes mellitus, fetal growth development and renal disease by food chain or water cycle (Talaska, 2003

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