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[29] Withdrawal symptoms from nicotine use (APESCGIT) are largely attributed to the activity of nAChRs, the primary targets for nicotine and the endogenous neurotransmitter acetylcholine

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Ed Miller, the former Maine American Lung Association executive director, said that based on past experience in Maine and other states, its not true that people will flock to New Hampshire to purchase tobacco

"It's a new product, and there's still a lot we don't know," says Pallav Pokhrel, a public health scientist at the University of Hawaii Cancer Centre