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Tobacco smoke contains thousands of harmful chemicals which hit a whole heap of ageing mechanisms in your body: Tobacco smoke speeds up the production of an enzyme which destroys collagen in your skin, the scaffold that holds your cells up and keeps skin firm and elastic

This can damage collagen production, slow healing times, and worsen inflammatory acne skin conditions

Today, one would be hard pressed to find anyone unaware of the risks of smoking, but despite that and billions in funding tobacco-prevention, the declines in smoking tapered off and flatlined during the mid-to-late 2000s with a stubborn 20-21 percent of adults either unable or unwilling to quit

Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights